11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
CAS: 28797-48-0
Molecular Formula: C14H10ClN3O2
11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one - Names and Identifiers
11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one - Physico-chemical Properties
| Molecular Formula | C14H10ClN3O2 |
| Molar Mass | 287.7 |
| Density | 1.415 |
| Boling Point | 481.1°C at 760 mmHg |
| Flash Point | 244.7°C |
| Vapor Presure | 2.06E-09mmHg at 25°C |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.637 |
11-(chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one - Introduction
11-(chloroacetyl)-5,11-dihydro-6h-pyrido [2,3-b][1,4]benzodiazepin-6-one is an organic compound with multiple hydrogen bonds and a heterocyclic structure. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: White solid
-Molecular formula: C17H11ClN2O2
-Molecular weight: 316.73g/mol
-Melting point: about 160-162 ° C
-Solubility: Soluble in organic solvents such as chloroform, dimethyl sulfoxide and dichloromethane, insoluble in water.
Use:
11-(choroacetyl)-5,11-dihydro-6h-pyrido [2,3-b][1,4]benzodiazepin-6-one is an effective intermediate commonly used in the synthesis of drugs and pesticides. Its derivatives have a wide range of biological activities and can be used in the research and development of anti-cancer, anti-virus and other drugs.
Method:
A common synthesis method is to obtain 5 by reacting chloroacetic acid with the corresponding 1,4-diazepine, 11-Dihydro-6H-pyrido [2.3-B][1,4] benzodiazepin-6-one, which is then reacted with Chloroacetyl Chloride to give the desired product. The specific preparation method can refer to the relevant research literature or patent documents.
Safety Information:
When handling 11-(chloroacetyl)-5,11-dihydro-6h-pyrido [2,3-b][1,4]benzodiazepin-6-one, the following safety measures should be observed:
-Avoid contact with skin, eyes and respiratory tract. In case of accidental contact or inhalation, rinse immediately with plenty of water and seek medical help.
-Wear suitable personal protective equipment such as protective gloves, glasses and face shields during operation.
-Avoid open flames and high temperature conditions to prevent the risk of burning and explosion.
-Storage should be sealed and kept away from fire and oxidizing agents.
-If there is no training or proper laboratory conditions, synthesis and use are not recommended. Consult a professional and follow the relevant laboratory safety procedures before operating.
Nature:
-Appearance: White solid
-Molecular formula: C17H11ClN2O2
-Molecular weight: 316.73g/mol
-Melting point: about 160-162 ° C
-Solubility: Soluble in organic solvents such as chloroform, dimethyl sulfoxide and dichloromethane, insoluble in water.
Use:
11-(choroacetyl)-5,11-dihydro-6h-pyrido [2,3-b][1,4]benzodiazepin-6-one is an effective intermediate commonly used in the synthesis of drugs and pesticides. Its derivatives have a wide range of biological activities and can be used in the research and development of anti-cancer, anti-virus and other drugs.
Method:
A common synthesis method is to obtain 5 by reacting chloroacetic acid with the corresponding 1,4-diazepine, 11-Dihydro-6H-pyrido [2.3-B][1,4] benzodiazepin-6-one, which is then reacted with Chloroacetyl Chloride to give the desired product. The specific preparation method can refer to the relevant research literature or patent documents.
Safety Information:
When handling 11-(chloroacetyl)-5,11-dihydro-6h-pyrido [2,3-b][1,4]benzodiazepin-6-one, the following safety measures should be observed:
-Avoid contact with skin, eyes and respiratory tract. In case of accidental contact or inhalation, rinse immediately with plenty of water and seek medical help.
-Wear suitable personal protective equipment such as protective gloves, glasses and face shields during operation.
-Avoid open flames and high temperature conditions to prevent the risk of burning and explosion.
-Storage should be sealed and kept away from fire and oxidizing agents.
-If there is no training or proper laboratory conditions, synthesis and use are not recommended. Consult a professional and follow the relevant laboratory safety procedures before operating.
Last Update：2024-04-09 19:05:48
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Product Name: 11-(Chloroacetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one Visit Supplier Webpage Request for quotation
CAS: 28797-48-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 28797-48-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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